After an overnight fast and sedation with subcutaneous acepromazine (0.1 mg/kg), anesthesia was induced with 5 mg/kg intravenous propofol, the trachea was intubated, and the lungs were ventilated with a mixture of 30% oxygen, .... First, CW002 is roughly five times more potent in dogs than in nonhuman primates,4 an animal model that may be more appropriate for predicting potency in human. Although the precise reason for this difference in potency is unclear, ...
Full article Panadeine Plus